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Transcranial Doppler measurement of middle cerebral arteryblood flow velocity: A validation study

Transcranial Doppler measurement of middle cerebral arteryblood flow velocity: A validation study.

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The reported ef?cacy of this treatment is slower com-pared to enzyme replacement therapy; thus it is indicated in patients presenting astable clinical condition under enzyme replacement therapy. Increases in NOS expres-sion have been observed in the hyperoxia model,although some have suggested that NOS dys-function may contribute to its pathophysiology,perhaps due to inadequate substrate (Vadivel etal. Also, when con-sidering the clinical relevance of Pin1 deregulation it should be kept in mind thatPin1 may also collaborate with mechanisms of tumor suppression as for examplep53- or p73- induced apoptosis [ 67 , 73] as well as degradation of CMYC [ 74 ] andCCNE [ 75]. Common locations includethe anterior communicating artery (30%), the internalcarotid artery (ICA) at the posterior communicating arteryorigin (25%), and the middle cerebral artery (MCA) bifur-cation (20%)

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